I-Evonik's Pharmaceutical-Grade AEROSIL® 200 Pharma: I-Nano-Scale Carrier Innovation for Global Drug and Food Industries

I-Evonik's Pharmaceutical-Grade AEROSIL® 200 Pharma: I-Nano-Scale Carrier Innovation for Global Drug and Food Industries

 

Ephreli 10, 2025, Hanau, Germany - U-Evonik, umholi womhlaba kumakhemikhali akhethekile, namuhla umemezele ukuthi umkhiqizo wawo osezingeni lezemithi i-AEROSIL® 200 Pharma (CAS No.: 112945-52-5) uthole izimvume zokulawula emazweni ayi-12, okubandakanya i-EU, i-US, kanye ne-Japan, i-US, kanye ne-Japan carrier ekhethwayo. kanye nezithasiselo zokudla emhlabeni wonke. Le silica ye-colloidal ehlanzekile kakhulu inikeza izixazululo eziphumelelayo zokuzinza kwezidakamizwa nokuphepha kokudla ngesakhiwo sayo se-nano-porous kanye nokuhambisana ne-multi-pharmacopeia.

 

I. Okugqamile Komkhiqizo: Ikhwalithi Yebanga Lezemithi & Nokusebenza Okuningi

 

I-AEROSIL® 200 Pharma iyi-amorphous anhydrous colloidal silicon dioxide ekhiqizwa nge-flame hydrolysis, equkethe:

 

- I-Ultra-High Purity: Okuqukethwe kwe-SiO₂ ≥99.0% (i-Ph. Eur. standard), enokulawula okuqinile kwezinsimbi ezisindayo (≤25ppm), i-arsenic (≤8ppm), nokunye ukungcola, okuthobelana nezimfuneko ze-EU E551 zokungeza ukudla.

- Isakhiwo Senethiwekhi Ye-Nano-Scale: Indawo eqondile engu-175-225 m²/g kanye nokuminyana kwe-tamped engu-50 g/L kuqinisekisa ukukhangiswa okuphumelelayo nokuhlakazeka okufanayo, okuthuthukisa ukutholakala kwezidakamizwa.

- Ukuthobelana kwe-Multi-Pharmacopeia: Kuqinisekiswe yi-European Pharmacopeia (Ph. Eur.), i-US Pharmacopeia (USP/NF), i-Japanese Pharmacopeia (JP), ne-Indian Pharmacopoeia (IP), esekela ukubhaliswa kwezidakamizwa emhlabeni jikelele.

 

II. Amapharamitha Obuchwepheshe & Ukuqhathanisa Ukusebenza

 

Inkomba AEROSIL® 200 Pharma Traditional Pharmaceutical Carriers

Specific Surface Area (BET) 175-225 m²/g 50-100 m²/g

Ukulahlekelwa Ekumisweni (105℃, 2h) ≤2.5% ≤5.0%

I-pH Inani (Uhlelo Olunamanzi) 3.5-5.5 6.0-7.0

Imikhawulo yeMicrobial (TAMC/TYMC) ≤1000 CFU/g ≤1000 CFU/g

 

III. Izimo Zohlelo lokusebenza Nenani Lomkhakha

 

1. Imboni Yezemithi

 

- Imithamo eqinile:

- Amathebulethi/Amaphilisi: Ithuthukisa ukugeleza kwempushana (inciphisa i-angle yokuphumula ngo-20-30%), ivimbela ukwakheka, futhi ithuthukisa ubulukhuni bethebhulethi (ngo-15-20%) kanye nokumelana nokuqina.

- Ukucindezelwa Okuqondile: Yehlisa ukusetshenziswa kwe-lubricant futhi ifinyeze imijikelezo yokukhiqiza.

- Amafomula we-Liquid:

- Ukumiswa / ama-Emulsions: Isebenza njenge-thickener kanye ne-thixotropic agent ukuvimbela ukuchithwa kwezidakamizwa (i-sedimentation volume ratio>95%).

- Imijovo: Ihambisana nezindinganiso ze-IPEC-GMP zokwenziwa kwe-aseptic.

 

2. Ukudla & Nutraceuticals

 

- I-Anti-Caking Agent: Igcina ukugeleza kokudla okuyimpuphu (isb., impushana yobisi, i-protein powder) ngaphandle kwekhekhe izinyanga ezingu-6+ ngaphansi komswakama ongu-≤60%.

- Isithwali Sezithako Esisebenzayo: I-Adsorbs amavithamini, ama-probiotics, njll., inweba impilo yeshalofu (ukugcinwa kwe-bioactivity kukhuphuke ngo-30%).

 

IV. I-Global Footprint & Ukusimama

 

I-Evonik iqinisekisa ukuhlinzekwa kwasendaweni kwe-AEROSIL® 200 Pharma ngokusebenzisa izindawo zokukhiqiza e-Hanau, eJalimane nase-Shanghai, e-China, enamandla onyaka angama-5,000 metric tons. Inqubo yokukhiqiza ibambelela ezinhlelweni ze-GMP ne-HACCP, kanti izinhlelo zokusimama zihlanganisa:

 

- I-Energy Recycling: Isebenzisa ukushisa okuyimfucuza ukukhiqiza amandla, kunciphisa ukusetshenziswa kukaphethiloli.

- Ukuthuthukisa Ukupakisha: Isebenzisa izikhwama zamaphepha ezinezingqimba eziningi ezigaywa kabusha (10 kg/isikhwama) ukuze kuncishiswe udoti wepulasitiki.

 

V. Ukwesekwa Kwamakhasimende Nezindaba Zempumelelo

 

- Amasevisi Ezobuchwepheshe: Ithimba lomhlaba wonke lochwepheshe abangu-200+ linikeza ukwesekwa okugcwele, okuhlanganisa:

- Isiqondiso sokuhlakazeka (kunconyiwe ukuxutshwa kwe-high-shear ≥30 imizuzu).

- Ukuhlolwa kokuhambisana (idatha ye-adsorption isotherm nama-API).

- Amaklayenti Abalulekile:

- Izinkampani Zemithi Yamazwe Ngamazwe: Zisetshenziswa kumaphilisi akhishwa njalo, azuza ukufana kokuqedwa (RSD <5%).

- I-Food Conglomerates: Impilo yeshelufu enwetshiwe yama-probiotic kusuka ezinyangeni eziyisi-6 kuye kweziyi-12 njengenkampani yenethiwekhi.

 

VI. Ulwazi lokuxhumana

 

- Iwebhusayithi yomhlaba wonke: www.silica-specialist.com

- Imibuzo Yezobuchwepheshe: technical.service.aerosil@evonik.com

- Inombolo yocingo yaseChina: +86 21 6119-1151

 

Mayelana no-Evonik

I-Evonik iyinkampani ehamba phambili yamakhemikhali akhethekile emhlabeni wonke enesipiliyoni seminyaka engu-50 ezinkampanini ezithwala imithi, isebenzela izinkampani eziyi-18 kwezingu-20 ezihamba phambili emhlabeni. Uchungechunge lwayo lwe-AEROSIL® lubamba ingxenye yemakethe yomhlaba wonke engu-35% ku-silica yezinga lezemithi, oluqhuba uguquko oluqhubekayo kubuchwepheshe bokulethwa kwezidakamizwa.

 

Qaphela: Ukusebenza komkhiqizo kungase kwehluke ngokusekelwe ekwakhiweni nasezimo zenqubo. Ukuhlola ukuhambisana kuyanconywa ngaphambi kokusetshenziswa. U-Evonik unelungelo lokushintsha imingcele yezobuchwepheshe ngaphandle kwesaziso sangaphambili.