Patent Implemented! Shandong Zhonglian Chemical's Colloidal Silica Purification Technology Empowers Upgrade of High-End Food and Pharmaceutical Excipients

Patent Implemented! Shandong Zhonglian Chemical's Colloidal Silica Purification Technology Empowers Upgrade of High-End Food and Pharmaceutical Excipients

Recently, the "colloidal silica purification device" patent technology (Publication No.: CN 111847461 A) developed by Shandong Zhonglian Chemical Co., Ltd. has been officially put into application. This technology specifically addresses the production pain points of high-purity colloidal silica in the fields of high-end food additives and pharmaceutical excipients, providing safe and efficient core material solutions for both sectors.

As a key excipient in the high-end food and pharmaceutical fields, the purity of colloidal silica is directly related to product safety and performance—food products need to avoid metal impurities affecting edible safety, while the pharmaceutical field has stricter requirements for low impurities and high stability in line with pharmacopoeial standards. Traditional precipitation processes have problems such as difficulty in removing metal impurities and sensitivity to operating parameters, making it difficult to meet the needs of high-end applications. The patented technology developed by Shandong Zhonglian Chemical innovatively adopts a combined process of chelating agent and spray acidification. Through the efficient capture of harmful metal ions such as Ca²⁺ and Fe³⁺ in raw materials by the chelating agent, combined with the rapid reaction characteristics of spray acidification, impurity residues are reduced from the source, enabling the product purity to meet the core requirements of food-grade and pharmaceutical-grade standards. At the same time, the technology expands the allowable fluctuation range of reaction temperature to ±5℃, greatly improving the stability and controllability of industrial production.

In the high-end food field, the colloidal silica produced by this technology can be used as a safe and efficient anti-caking agent and flow aid, widely applied in products such as protein powder, spice premixes, dairy products, and baked goods. It can effectively prevent raw material caking and adhesion, extend the shelf life, while ensuring food taste and safety. In pharmaceutical excipient applications, its advantages of high purity and good biocompatibility are particularly prominent. It can be used as a glidant, lubricant, and excipient in pharmaceutical formulations, optimizing the tableting efficiency and uniformity of tablets, promoting drug disintegration and sustained release, enhancing efficacy while reducing side effects. It is suitable for various dosage forms such as tablets, capsules, and ointments, fully complying with the strict specifications for pharmaceutical excipients in pharmacopoeial standards.

With the upgrading of consumers' pursuit of food health and the high-quality development of the pharmaceutical industry, the market demand for high-end food additives and pharmaceutical excipients continues to grow. The implementation of this patented technology not only fills the gap in domestic high-end colloidal silica purification processes but also breaks the dependence on imported materials in high-end fields. It injects core technical momentum into the upgrading of China's food and pharmaceutical industries, helping related industries achieve dual improvements in safety quality and production efficiency.